New COVID variant

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What is the new variant and why is it a concern?
Scientists have detected a new Covid-19 variant called B.1.1.529 and are working to understand its potential implications. About 50 confirmed cases have been identified in South Africa, Hong Kong and Botswana.

B.1.1.529 has a very unusual constellation of mutations, which are worrying because they could help it evade the body’s immune response and make it more transmissible, scientists have said. Any new variant that is able to evade vaccines or spread faster than the now-dominant Delta variant might pose a significant threat as the world emerges from the pandemic.



Where exactly has it been found?
Early signs from diagnostic laboratories suggest the variant has rapidly increased in the South African province of Gauteng and may already be present in the country’s other eight provinces.

In a regular daily update on confirmed cases nationally, the National Institute for Communicable Diseases (NICD) reported 2,465 new Covid-19 infections, slightly less than double the previous day’s infections. The NICD did not attribute the latest resurgence to the new variant, although some leading local scientists suspect it is the cause.

South Africa has confirmed about 100 specimens as B.1.1.529 but the variant has also been found in Botswana and Hong Kong, with the Hong Kong case a traveller from South Africa. As many as 90% of new cases in Gauteng could be B.1.1.529, scientists believe.

How does it compare to other variants?
Senior scientists on Thursday evening described B.1.1.529 as the worst variant they had seen since the start of the pandemic. It has 32 mutations in the spike protein, the part of the virus that most vaccines use to prime the immune system against Covid. That is about double the number associated with the Delta variant. Mutations in the spike protein can affect the virus’s ability to infect cells and spread, but also make it harder for immune cells to attack the pathogen.
https://www.theguardian.com/world/2021/nov/25/what-do-we-know-about-the-new-worst-ever-covid-variant
 
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