If you ever took mushrooms, maybe you were onto something...

Linus

Member
Psilocybin Causes ‘Significant Reduction’ in Symptoms of Depression, Largest of its Kind Study Shows




Psychedelics are being seriously researched for a host of medicinal effects.


Classic” Psychedelics Defined


  • Those substances that have their primary mechanism of action on serotonin 2a receptors in the brain
    • LSD
    • Psilocybin (magic mushrooms)
    • Mescaline (active in peyote)
    • DMT (ayahuasca)

How can they help?


  • Neural rewiring
  • Default mode network activity reduction
  • Shifts in perception or perspective – epiphany
    • A true sense of Awe
    • Change the way you view reality after the experience

Evidence and research studies with psychedelics



There you go, to name a few. I'm particulary interested in the research on DMT and the experiences people have had on this drug.
 

HBS Guy

Head Honcho 💉💉
Staff member
Revelations was written by someone on magic mushrooms I reckon!

Your god was crucified and your temple and city dismembered you could use a little chemical help?
 

Linus

Member
Something on DMT

"One of the most promising and compelling advantages of DMT research is that experts report that when done correctly, DMT can help address the root causes of issues like depression, anxiety, and substance abuse.

This contrasts directly with current psychiatric responses to mental health conditions like depression, which frequently simply treat the symptoms of the depression (with things like antidepressants or benzodiazepines).

It goes without saying that having a reliable way to help people process the initial trauma that led to their current experience of addiction, illness, mental health disorders, and more — would be more than just groundbreaking. It would be revolutionary.

The mysteries of DMT research

When it comes to DMT and other psychedelics, there are still a lot of compelling questions yet to answer. For example, while scientists know that the human body shows differing levels of DMT, it’s unclear what DMT is doing there.
It’s obviously important, since it’s one of the rare compounds the brain absorbs that cannot be generated by the body itself (other compounds like this include amino acids required for healthy brain functioning, and glucose).

“That makes you wonder if DMT might be involved in the regulation in every day normal consciousness as well,” says Dr. Strassman. “And something else that has been discovered over the past few years is that the enzyme and the gene that synthesise DMT are quite active in the retina. So it could be that DMT is regulating a visual perception in particular as well as regulation of consciousness.”

According to Dr. Stassman, “I think DMT in particular, but psychedelics in general, must likely stimulate the imaginative faculty of the mind more than the rational faculty … So it could be that once we start looking at the biology or the neurophysiology of the imaginative faculty versus the rational faculty, DMT may help us understand the imaginative faculty’s function.”

In other words, psychedelics like DMT could help us understand what exactly the human imagination is, and what its purpose is. Again, part of its purpose could be profound healing.

The future of DMT research

One challenge in terms of researching the effects of DMT is that the body breaks it down quickly. Typically a DMT “trip” only lasts 15-30 minutes.
However, in 2016 Dr. Strassman and colleague Andrew Gallimore published new research outlining a methodology for giving DMT continuously over a number of hours, extending a person’s experience.

The purpose of the study was in part to explore the possibility of using DMT therapeutically. “Lots of people describe the therapeutic benefits of ayahuasca,” says Strassman, “and if you could extend the DMT state you could be able to apply it for therapeutic purposes. More practical experiments would be to extend the state and see if that has applications for therapy.”

And according to Rick Doblin, TED speaker and head of the organization MAPS (Multidisciplinary Association for Psychedelic Studies), “In the work with classic psychedelics such as LSD and psilocybin, for example, what we’ve discovered is the mystical experience you can have — the depth of ego dissolution — is correlated with therapeutic outcomes. The more people go beyond themselves into this sort of state, the better they’re able to overcome their fear of death, overcome addiction, or overcome depression.”
Doblin and other leaders in the field are outspoken about the need to legalize psychedelics, so that more people can be helped faster."


Intriguing, isn't it?
 

mothra

Moderator
Staff member
There is so many magnitudes of interesting stuff about fungi.

Also, about the use of psychotropics for various mental health conditions.

Did you know that a single therapeutic dose of MDMA has been found in repeated clinical trials to cause the cessation of major symptoms for people with PTSD for 3 months?

But behold! Red tape.

Anyway, back on funghi, there is a FAN-FUCKING-TASTIC doco on Netflix called "Fantastic Fungi". Honestly, it's just amazing. Super-highly recommend it.
 

HBS Guy

Head Honcho 💉💉
Staff member
The mycorrhizal fungal networks that link the feeder roots of trees, linking those trees—one tree feels stress for some reason, the byproducts of that stress travel the fungal network and the other trees prepare for that stress—cooperation between totally different types of trees in a copse or part of forest or jungle! Not just endless competition to grow tallest to get all the light possible.

Wholesale spraying of sulphur (bordeaux mixture, straight sulphur for mold etc) will kill these fungal networks and your trees will not benefit from the symbiosis of mycorrhizal fungi. Mild leaf curl in peach, nectarine trees—just let the affected leaves fall off, healthy leaves will replace them. Need to spray—cover the ground with tarps, remove the tarps when the sulphur is used up/washed off etc.
 
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